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2025-03-14

[YouTube] The Base Rate Fallacy in Cardiology with respect to LDL

People with normal Lp(a) have much lower risk factors. We tend to overmedicate them. The normal levels of LDL should be revised upwards for them. The post [YouTube] The Base...

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Trump Changes EPA Rules to Allow Vastly More Pollution

As expected, the Trump administration is massively rolling back environmental protection policies, accelerating an already heated race to the bottom. Trump's appointed Environmental Protection Agency leader Lee Zeldin announced 31...

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This One Goes to 27

On this day 27 years ago, on March 14, 1998, I started this here website. Iā€™m not sure what there is to say about the ridiculous length of time that...

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The Legend of Larry Owl

Paul Kafasis, on a seemingly local-to-Boston Genmoji billboard from Apple: Eventually, though, the penny dropped. After my umpteenth time passing the billboard, while trying to distract myself from the single-digit...

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Wired has a big story (150+ sources) that takes a look Inside...

Wired has a big story (150+ sources) that takes a look Inside Elon Muskā€™s ā€˜Digital Coupā€™. ā€œThe next step: Unleash the AI.ā€ šŸ˜±

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Sarah Wynn-Williamsā€™s memoir about working at Facebook, Careless People: A Cautionary Tale...

Sarah Wynn-Williamsā€™s memoir about working at Facebook, Careless People: A Cautionary Tale of Power, Greed, and Lost Idealism (Bookshop), is on the bestseller charts after Meta tried to get the...

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How Sustainable Are Web3 Game Economies? Sugarverse Raises $1 Million to Prove It

Sugarverse secures $1 million to develop Web3 games with lasting economies, starting with Sugar Match on Tezosā€™ Etherlink in 2025.

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Anthropic CEO Suggests That AI Deserves Workers' Rights

Let's assume that AI technologies have progressed to the point where models have become near indistinguishable from human consciousness. What would happen if we were to give a highly-advanced AI...

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Ted Lasso is returning for a fourth season. Not every actor is...

Ted Lasso is returning for a fourth season. Not every actor is on board (yet)ā€¦itā€™ll be interesting to see where this goes. šŸ’¬ Join the discussion on kottke.org ā†’

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U.S. Lawmakers Urge U.K. Secretive Investigatory Powers Tribunal to Hold Public Hearing Regarding Demand for Secret iCloud Backdoor

Zack Whittaker, reporting for TechCrunch: A group of bipartisan U.S. lawmakers are urging the head of the U.K.ā€™s surveillance court to hold an open hearing into Appleā€™s anticipated challenge of...

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Trailer for season two of Poker Face. If you havenā€™t seen it,...

Trailer for season two of Poker Face. If you havenā€™t seen it, itā€™s directed by Rian Johnson (Knives Out/Glass Onion) and Natasha Lyonne plays an itinerant Benoit Blanc sort of...

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Web3 is an Evolution in Emerging Markets, Says Igor Kucherenko

Co-founder of HitBit Pro and Head of Pateplay Africa believes that Web3 is a revolution in emerging markets, allowing people to safely make payments and preserve capital.

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Bill Gates Gives Up on Climate Change

In decades past, as the effects of climate change slowly became undeniable,Ā some looked to the super rich for answers ā€” the billionaires with enough cash to really make a...

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From One-Off Transactions to Intelligent Payments: The Evolution of Open Banking with VRP

Open Banking began as a response to the European Unionā€™s PSD2 regulation, designed to increase competition and innovation in financial services. Open Banking enabled third-party providers to introduce new payment...

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React vs. Vue vs. Angular: Which Framework is Best for Developers in 2025?

React: Flexible, library-focused approach. Great for projects that need customizable solutions. Vast ecosystem but requires additional libraries for routing and state management. Vue: Easy to learn, uses single-file components, and...

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Create A Lightning Text Effect Using HTML And CSS Using This Simple Code

This tutorial demonstrates how to create a striking lightning text effect using HTML and CSS. By structuring the HTML with a container and child elements, and applying specific CSS properties...

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How to Adjust Your Mac's Energy Saver Settings to Keep It Awake For Longer

Have you ever been in the middle of an important task, only for your Mac to dim the screen or go to sleep at the worst possible moment?

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AIā€™s Energy Dilemma: Can LLMs Optimize Their Own Power Consumption?

The debate concerning the sustainability of the AI has become increasingly important. The training phase remains the biggest contributor to power consumption in AI systems. Pruning and self-optimization approaches are...

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Food for Agile Thought #484: Vibe Coding, Productā€™s Hard Nature, Brittle Product Teams, Pivots & Post-Mortems

TL; DR: Vibe Coding ā€” Food for Agile Thought #484 Welcome to the 484th edition of the Food for Agile Thought newsletter, shared with 42,673 peers. This week, Ethan Mollick...

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Big Tech Loves These 45 System Design Questionsā€”Do You Have the Answers?

With system design, you never know whatā€™ll be asked. Which makes it hard to practice.

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